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Full Length de novo Gene Synthesis with Free Codon Optimization   

Various Types of Services Available to Help Balancing Your Needs and Budget.

Accommodates Hundreds of Projects Simultaneously.

Recent Publications Citing Our Gene Synthesis Service

A Partial List of Our Customers

  • Full Service: $0.45/bp, summer rate for first time customers. Cloned into our standard vector pBlueScript or pUC and sequence verified. Custom cloning into your own vector extra $250/each. Minimum order for each samll gene is $150.00. Guaranteed low price, email or call for quote. 
  • Gene Variants: As low as $149/per variant. Thousands of gene variants can be generated in very short time. Greatly facilitates systematic investigation of structure and function. Making your un-approachable projects realistic at minimal cost. 
  • Fragment Synthesis: $0.35/bp. Double stranded unphosphorylated, agarose gel-purified DNA fragment. Sequence *NOT* verified by sequencing. Ready to be cloned; Suitable for gene variant pool or library construction. Guaranteed enough for at least 10 independent subcloning. Free Resynthesis in case more material is needed. Under 7 days turn around time. Any size. High GC no problem. Recommended for genes < 850 bp.
  • Oligo Synthesis for Gene Construction: Single tube order: $0.20/base, 8 oligos minimum. Plate order: $0.17/base, 24 oligos minimum. Turn around time 4-5 days.
  • Optional codon optimization with no extra charges are included for both services.
  • Single-host vs. multi-host codon optimization for over-expression 
  • Complete sequencing* (for full service only), 100% accuracy
  • As fast as 6 days, on average 2-3 week turn around time**

Price Structure and Turnaround Time:

Price:  No set up fee, no hidden charges.

For a non binding quote of our Full Service for your particular project, email your sequence to  genesynthesis@epochbiolabs.com

Turnaround Time:

Under 7 business days for synthetic fragments. Full Serviced (cloned and sequence verified) are as follows:

Gene size  Average Turn Around Time***
< 1kp 6-12 business days
1-3kb 10-17 business days
3-10kb 15-25 business days

How to order:

Please follow these instructions closely to speed up your ordering process.

1. Call us (832-886-5231) or email us @, genesynthesis@epochbiolabs.com, your gene/protein sequence and particular manipulations you wish us to perform. Particularly give clear instructions on the following options: codon optimization vs. no optimization; host organisms; single host vs. multiple host optimization; restriction sites or flanking sequences need to be incorporated into both ends; restriction sites or flanking sequences need to be eliminated or avoided internal to the gene; codon usage table preferred and any other specific requirements.

2. Ask your purchasing department to fax us (832-886-5152) the valid purchase order number. Work only starts with an authorized purchase order number.

** Epoch Biolabs, Inc. adopt a non-disclosure policy to all of our customers. To protect your proprietary information please mail, email (legal@epochbiolabs.com) or fax (832-886-5152) your confidentiality agreement to us for sign. If intended, this should be done before any information is released to us. If you don't have your own NDA/confidentiality agreement,  you can find ours at here. Feel free to modify it to suit your specific needs.

*Double strand sequencing covers 100% of one strand and ~65% of the other strand. **Turn around time differs from size to size. Please refer to the table. ***Delivery schedule is affected by work load and waiting list. Email us for the earliest delivery date of your gene.

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