Various Types of Services Available to Help Balancing Your Needs and Budget.

Accommodates Hundreds of Projects Simultaneously.

Recent Publications Citing Our Gene Synthesis Service

A Partial List of Our Customers

Price Structure and Turnaround Time:

Price:
No set up fee, no hidden charges.

For a non binding quote of our Full Service for your particular project, email us at genesynthesis@epochbiolabs.com

$0.39/bp for synthetic fragment only. 

Turnaround Time:

Under 7 business days for synthetic fragments. Full Serviced (cloned and sequence verified) are as follows:

Introduction: 

Gene synthesis provides the freedom of creating any gene in the absence of genomic or cDNA. Extending the capability of oligonucleotide synthesis technology, gene synthesis is indispensable for new gene creation and artificial genome assembly. Gene synthesis involves multiple steps which, so far, precluded it from full automation. Epoch Biolabs' Custom Gene Synthesis Service implements rigorous standards and incorporates many innovations at each of the many steps: from computer aided gene design, high fidelity amplification, restriction site independent and size unlimited gene assembly to efficient subcloning, which makes our service the most reliable yet affordable custom DNA synthesis service among many competitors.

Applications: 

Gene synthesis has found wide applications in molecular biology and biomedical researches. From de novo gene synthesis, codon optimization for protein overexpression, site-directed mutagenesis to DNA vaccine optimization etc.

Often subcloning from cDNA is more difficult for rare genes with low copy number transcripts. Full length subcloning for larger genes is also problematic. At our ultra-low price, Epoch Biolabs' Contract Gene Synthesis Service is the ideal substitution for your tedious subcloning efforts. With double strand sequencing and 100% accuracy guarantee you would speed up your research by focusing on more challenging aspects of your project.

Genes of high commercial values and academic interests from bacteria living in extreme environments or from virulent pathogens are hard to obtain due to the limited sources for bacterial cultures. Again our custom gene synthesis service put your gene in your hand in just 3 weeks yet still within you tight budget. 

Biochemists who need milligrams of proteins for their studies and cell biologists who depend on a readable signal of their gene in transfected cell lines perfectly understand the problems brought by low expression levels. Among many contributing factors, codon frequency and rare codon usage have been proven to be one of the parameter results in low expression level. With Epoch Biolabs' customer DNA synthesis service you have the freedom of using the only most used codon for your particular expression host and have the potential of increasing your expression level. Furthermore, our gene synthesis service can provide you with a single gene fits multiple hosts expressions. Be it E.coli and insect cell expression, yeast and human or E.coli and mouse, you decide what you want and we make it possible for you. 

Are you a structural biologist trying hard to remove all of the cysteines from your favorite receptor or channel for a site-directed cysteine cross-link experiment? Still remove them one by one? We do it all the same time even with codon optimized at your option.

How to order:

Please follow these instructions closely to speed up your ordering process.

1. Epoch Biolabs, Inc. adopt a non-disclosure policy to all of our customers. To protect your proprietary information please mail, email (legal@epochbiolabs.com) or fax (832-886-5152) your confidentiality agreement to us for sign. If intended, this should be done before any information is released to us. If you don't have your own NDA/confidentiality agreement,  you can find ours at here. Feel free to modify it to suit your specific needs.

2. Call us (832-886-5231) or email us @, genesynthesis@epochbiolabs.com, your gene/protein sequence and particular manipulations you wish us to perform. Particularly give clear instructions on the following options: codon optimization vs. no optimization; host organisms; single host vs. multiple host optimization; restriction sites or flanking sequences need to be incorporated into both ends; restriction sites or flanking sequences need to be eliminated or avoided internal to the gene; codon usage table preferred and any other specific requirements.

3. Ask your purchasing department to fax us (832-886-5152) the valid purchase order number. Work only starts with an authorized purchase order number.

*Double strand sequencing covers 100% of one strand and ~65% of the other strand. **Turn around time differs from size to size. Please refer to the table. ***Delivery schedule is affected by work load and waiting list. Email us for the earliest delivery date of your gene.